Open Research Studies at the Penn Memory Center

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The Biogen study is a Phase II clinical research study of the drug aducanumab for individuals age 50-85 with early Alzheimer’s disease, including mild cognitive impairment.

Aducanumab is a human antibody that recognizes some forms of beta-amyloid. The primary objective of the study is to evaluate the efficacy of aducanumab in slowing cognitive and functional impairment. This drug is not FDA-approved and is investigational.

Click here for a one-page handout on Biogen.

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The Anti-Amyloid Treatment in Asymptomatic Alzheimer’s study (A4 for short), is a clinical research study for older individuals who may be at risk for Alzheimer’s disease (AD). The A4 study is investigating a drug intervention, solanezumab, and Individuals 65-85 years of age with normal cognition may be eligible. The study requires infusion visits every four weeks, for a total of 42 infusion visits over three consecutive years.

 

Download a one-page overview of this study including contact information

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The purpose of the ASL-PET study is to determine the value of a special MRI scan that measures cerebral blood flow (called Arterial Spin Labeled MRI) in the diagnosis of Mild Cognitive Impairment. We will compare this measure with other more established tests: brain imaging with Postiron Emission Tomography (PET/CT) and a lumbar puncture (LP) procedure, which allow researchers to evaluate the quantity of proteins associated with Alzheimer’s Disease.

Individuals 55-89 years of age with a diagnosis of Mild Cognitive Impairment (MCI) or normal controls may be eligible.

Download a one-page overview of the study, including contact information.

Welcome to Penn Memory Center

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Aging and Cognition: Maintaining Economic Security in Later Life

On May 9 and 10, the World Economic Forum’s Global Agenda Council on Ageing (WEF GAC) and the University of Pennsylvania’s Healthy Brain Research Center were pleased to host “Aging and Cognition: Maintaining Economic Security in Later Life,” the fourth and final symposium in a series presented by the WEF GAC.

The symposia intended to increase action and impact on innovative approaches in the financial services sector to overcome limitations of age-related cognitive decline. Outcomes of each symposium will be shared through comprehensive reports, feedback, and recommended actions for engagement.

Click here to learn more about each symposia and watch videos of most Philadelphia presentations.


News and Events

“Leah’s Legends,” a team of five talented friends of the Penn Memory Center, is set to debut its inaugural improv show
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Please join us for a special Memory Café night at the Penn Museum. At this free event, friends of the
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  A diagnosis of Alzheimer’s disease will not lead to a prescription for a “miracle cure,” but older adults with
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Tigist Hailu, Penn Memory Center coordinator for diversity in research and education, has successfully graduated from the University of Pennsylvania’s
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  Earlier this month, Penn Alzheimer’s Disease Core Center Director Dr. John Q. Trojanowski presented a lecture on “Experimental Transmission of
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Penn Memory Center in the Community

Click here to find out about the important work the Penn Memory Center is doing in the Philadelphia community.

 PMC in community

What does it mean to be a caregiver?

Click here to listen to the stories of caregivers from the PMC community.

I am a Caregiver

 

The University of Pennsylvania Prevention Research Center


The University of Pennsylvania Prevention Research Center seeks to advance public health goals, and serves as a hub for interdisciplinary chronic disease prevention research, training, and dissemination at the University of Pennsylvania.

Penn Memory Center's Jason Karlawish, MD, leads one of the PRC's Special Interest Projects - Alzheimer's/Dementia Assessment Messaging - and one of the SIP's Collaborating Networks - The Healthy Brain Research Center.

To read more about the PRC's work, visit their website at http://www.upennprc.org/