Director, Penn Memory Center
Dr. Steven E. Arnold is a Professor of Psychiatry and Neurology at the University of Pennsylvania Perelman School of Medicine, and Director of the Penn Memory Center. He is board certified in both psychiatry and neurology.
Dr. Arnold received his MD from Boston University. He completed a residency in Psychiatry at the New York State Psychiatric Institute / Columbia Presbyterian Medical Center, and in Neurology at the University of Iowa. He also completed a fellowship in Behavioral Neurology / Cognitive Neuroscience and was a post-doctoral associate in Neuroanatomy there.
His leadership roles include serving as: Associate Director and Clinical Core Leader of the National Institute on Aging-designated Alzheimer’s Disease Core Center; Director of the Geriatric Psychiatry Section in the Department of Psychiatry; Director of the Cellular and Molecular Neuropathology Program in the Center for Neurobiology and Behavior, and Associate Director of the University of Pennsylvania’s Institute on Aging (IOA).
Dr. Arnold has authored over 150 scientific articles and his research has garnered numerous awards. He is principal investigator for research spanning clinical trials, phenomenology and neuropsychology, molecular neuroimaging, biochemical biomarkers, epidemiology-scale molecular neuropathology in postmortem tissues, and rodent models of chronic stress effects on aging, behavior, and neuropathology. He has conducted longstanding studies into neurodegenerative disease pathology in relation to cognitive decline in late life, and he leads a broad clinical and translational research program examining brain and mind aging.
His major interests include clinical biomarker identification of neuropathology in the aging brain, the long-term neurobiological effects of stress, anxiety, and depression on memory and risk for dementia, and protective factors that account for cognitive resilience in aging. Dr. Arnold has also had longstanding interest in the neurobiology of severe mental illnesses and leads a clinicopathological and neurobiological studies program focused on the cellular, biochemical and molecular neuropathology of schizophrenia using human postmortem tissues.