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Scientists at 26 institutions across the nation are investigating the effects of Resveratrol, a compound found in red grapes, on healthy brain aging. In the "Red Wine Study" at Georgetown University Medical Center, doctors are investigating whether the compound can help to slow or stop the progression of Alzheimer's disease. Raymond Turner, MD, is leading the study at Georgetown, and he says that while researchers don't yet know exactly how Resveratrol works they believe it can activate a gene associated with brain aging. Georgetown is one of 26 institutions in the country participating in this study, and the Penn Memory Center at the University of Pennsylvania is one such institution. According to Patricia Martinez, study coordinator for the Resveratrol study at the Penn Memory Center, “Resveratrol, a compound found in the skin of red grapes and in dark chocolate, is being tested to determine if it can delay the progression of Alzheimer’s disease. Here at the Penn Memory Center we are conducting this study in order to evaluate the safety, tolerability and effectiveness of Resveratrol in people with mild to moderate Alzheimer’s disease."